Whatever Became of Hawaii’s First Test Tube Baby?

Jacquelyn Low’s historic birth made headlines across Hawaii and beyond 25 years ago. Now the University of Oregon alumna is preparing to move to China to continue her education.

Chris Fleck
Wednesday - June 29, 2011
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Baby Jacquelyn with proud parents Janice and James

exam. PIVF laboratory director Dr. Thomas Huang was working very closely with Janice Low’s laboratory fertilization in 1985.

“I remember seeing the lab sheet that came back with the beta eggs she gave us from the pregnancy hormone tests showing positives,” says Huang. “That was a day I’ll never forget.”

For Janice, it was the doctors of PIVF who made what was a tumultuous, anxious pregnancy experience a bit easier. As the first in vitro pregnancy in Hawaii, Janice says she was not treated normally by the original PIVF doctors, who included Thomas Kosasa, Philip McNamee, Francis Terada, Benton Chun. and Huang.


“When I had to go to the emergency room for labor, I remember Dr. Kosasa was on call and he asked everyone else not to touch me. I was a little special, they were extra cautious with me,” recalls Janice.

As IVF was such an radical procedure, that caution would remain even after healthy, 7 1/2-pound Jacquelyn was born.

So she certainly has an exceptional answer to the question, “Where do babies come from?”

(from left) Dr. Thomas Kosasa, Jacquelyn Low and Dr. Carl Morton. Nathalie Walker photo .(JavaScript must be enabled to view this email address)

Jacquelyn’s earliest memory surrounding her birth and in vitro fertilization was at a party held at Washington Place that celebrated the first 100 IVF babies born in Hawaii.

“I remember I was really young at the governor’s mansion, and a television reporter asking me what the party was for and I responded, ‘Test tube baby,’ so I have known for a while,” says Jacquelyn.

She also had to get used to the hovering from her parents and doctors.

“They were so overbearing, all of them,” she adds with a laugh. “The doctors would call me at night to make sure I went to sleep.”

Jacquelyn has grown to understand that the caution and protectiveness was out of love. For many women and couples who choose to have an IVF procedure, it is usually their last chance of getting pregnant, so when it is successful, the emotions run extra high.

The Star-Bulletin’s Page 1 story told the happy news

“When we had our first 100 babies party at the governor’s mansion, I know for a fact that every single set of parents was very special. There was no yelling or screaming. No threatening or spanking,” says Morton. “It was an absolute love fest toward the kids, and I think that is true with all IVF babies.”

Although showered with love from day one, Jacquelyn does admit there is a certain sense of pressure or expectation for IVF babies.

“If you think about all the success and failure talk about having a baby on that level, you have to think about how we feel as the baby. It is a lot of pressure, because all we want to do is make them happy - they brought life to us,” she says.

Janice and James only want the best for Jacquelyn, and she continues to make them proud. She graduated from Iolani, then continued her education, graduating in 2008 from University of Oregon with a bachelor’s degree in business administration and a minor in Chinese. In August, Jacquelyn will move to Guangzhou, China, for one year to study through UH Manoa’s Shidler Business School’s MBA program.

Just as Jacquelyn is coming of age, maturing before her parents’ eyes, the developments of in vitro fertilization have been vastly improving over the past 25 years. The IVF procedure has since become much easier on women. What used to be a laparoscopic procedure conducted under general anesthesia, which required some recovery time, is now a general out-patient procedure with women being released only hours after their eggs are removed.

“Back in the ‘80s the woman had to stay flat on her back, tilted backwards. We’ve learned a lot more about the conditions of the eggs and embryos and what they need to develop, so I would say the dramatic changes have been in the laboratory,” says Huang.

Jacquelyn at age 5. Photo courtesy Low family

Success rates of IVF are usually determined by the age of the patient, with women under the age of 35 having a more successful chances of pregnancy because of the quality of their eggs. In the ‘80s, the success rates was about 20 percent. Now those percentages are around 50 percent. That may not sound like a significantly high percentage, but to many infertile women faith can be found in even a 1 percent chance.

Collaboratively working with Galileo Research Laboratories, an international consulting group, as well as Dr. Yanagimachi and many other doctors and students at UH Manoa’s Institute for Biogenesis Research, developments in Advanced Reproductive Technology (ART) Services are constantly evolving. Specifically, procedures in egg freezing now give women a chance to freeze their unfertilized eggs for when they are more prepared for pregnancy. This procedure also is extremely important to women who may have to undergo certain cancer treatments that could compromise their egg quality. Intracytoplasmic Sperm Injection, or ICSI, is another revolutionary change developed to help couples with severe male factor infertility. Financially, steps are being taken, giving patients the means to follow through with IVF procedures. In 1987, a Hawaii state law mandated that any insurance that covers obstetrical care must cover one attempt by IVF.


As the first, Jacquelyn Low is a story of personal accomplishment and continuing success. But this also is a story of hope and possibility for all women and couples who have that yearning to bring their own child into our world, surrounding a young baby girl or boy with love, guidance and security.

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